Which two proteins are examples of antimicrobial proteins (AMPs)?

Which two proteins are examples of antimicrobial proteins (AMPs)?

• A. Defensins and Thrombocidin
• B. Interferons and Defensins
• C. Lactoferrin and Ferritin
• D. Histamine and Prostaglandins

Answer: (A)

Defensins and Thrombocidin are both recognized as antimicrobial proteins (AMPs). Defensins are small peptides produced by various cells in the human body, including neutrophils and epithelial cells, that possess the ability to disrupt microbial membranes, leading to the death of bacteria and fungi. This makes them key players in the innate immune response by providing a first line of defense against invading pathogens.

Thrombocidin, on the other hand, is a peptide that is derived from platelets and exhibits antimicrobial properties by directly killing bacteria. It plays a role in the host's defense mechanism, particularly in the context of wound healing and preventing infections following tissue damage.

The selection of these two proteins highlights the diverse strategies that the body employs to combat infections, as both defensins and thrombocidin actively target and neutralize potential microbial threats.